Sorbic acid
Tocris Bioscience, part of Bio-Techne | Catalog # 7119
Activator of hFFA2-DREADDs
Discontinued Product
7119 has been discontinued.
View all DREADD Activators products.
Product Description
Sorbic acid is an activator of hFFA2-DREADDs. Inhibits forskolin-induced cAMP production (IC50 ∼ 1 μM) and promotes accumulation of inositol monophosphates (IC50 >1 μM) in cells expressing hFFA2-DREADD. Promotes the release of GLP-1 from colonic crypts derived from hFFA2-DREADD-expressing mice.Product Specifications
Molecular Weight
112.13
Formula
C6H8O2
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
(2E,4E)-2,4-Hexenoic acid
CAS Number
110-44-1
PubChem ID
643460
InChI Key
WSWCOQWTEOXDQX-MQQKCMAXSA-N
SMILES
CC=CC=CC(=O)O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 11.21 | 100 | |
| Ethanol | 11.21 | 100 |
Preparing Stock Solutions
for Sorbic acid
The following data is based on the product molecular weight 112.13
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 8.92 mL | 44.59 mL | 89.18 mL |
| 5 mM | 1.78 mL | 8.92 mL | 17.84 mL |
| 10 mM | 0.89 mL | 4.46 mL | 8.92 mL |
| 50 mM | 0.18 mL | 0.89 mL | 1.78 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bolognini Chemogenetics defines receptor-mediated functions of short chain free fatty acids. Nat.Chem.Biol. 2019 PMID: 30992568
Product Specific Notices for Sorbic acid
For research use only
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