Sodium Cromoglicate
Tocris Bioscience, part of Bio-Techne | Catalog # 6424
Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells
Key Product Details
Description
Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells
Product Description
Sodium Cromoglicate is a promotes transformation ESCs/iPSCs into pancreatic endocrine islet cells. Facilitates differentiation from endocrine precursors. Also inhibits mast cell degranulation and histamine release. Antiasthmatic.Product Specifications
Molecular Weight
512.33
Formula
C23H14Na2O11
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
5,5'-[(2-Hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-4H-1-benzopyran-2-carboxylic acid] disodium salt
CAS Number
15826-37-6
PubChem ID
27503
InChI Key
VLARUOGDXDTHEH-UHFFFAOYSA-L
SMILES
OC(COC1=C2C(C=C(C(O[Na])=O)OC2=CC=C1)=O)COC3=C4C(C=C(C(O[Na])=O)OC4=CC=C3)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 25.62 | 50 |
Preparing Stock Solutions
for Sodium Cromoglicate
The following data is based on the product molecular weight 512.33
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 3.90 mL | 19.52 mL | 39.04 mL |
| 2.5 mM | 0.78 mL | 3.90 mL | 7.81 mL |
| 5 mM | 0.39 mL | 1.95 mL | 3.90 mL |
| 25 mM | 0.08 mL | 0.39 mL | 0.78 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Kondo Identification of a small molecule that facilitates the differentiation of human iPSCS/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells. Diabetologia. 2017 PMID: 28534195
- Orr and Cox Disodium Cromoglycate, an inhibitor of mast cell degranulation and histamine release induced by phospholipase A. Nature. 1969 PMID: 4183038
Product Specific Notices for Sodium Cromoglicate
For research use only
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