SNC 162
Tocris Bioscience, part of Bio-Techne | Catalog # 1529
Potent, selective non-peptide δ agonist
Key Product Details
Description
Potent, selective non-peptide δ agonist
Product Description
SNC 162 is a potent and selective non-peptide δ-opioid receptor agonist (Ki = 0.63 nM). Displays > 8000-fold selectivity over μ-opioid receptors and is centrally active following systemic administration in vivo.Product Specifications
Molecular Weight
419.61
Formula
C27H37N3O
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide
CAS Number
178803-51-5
PubChem ID
6604878
InChI Key
WGIDFDFAOQVAHY-UFPGJGBJSA-N
SMILES
[H][C@@](C2=CC=CC=C2)(N3C[C@@H](C)N(CC=C)C[C@@H]3C)C1=CC=C(C(N(CC)CC)=O)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1eq. HCl | 41.96 | 100 |
Preparing Stock Solutions
for SNC 162
The following data is based on the product molecular weight 419.61
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.38 mL | 11.92 mL | 23.83 mL |
| 5 mM | 0.48 mL | 2.38 mL | 4.77 mL |
| 10 mM | 0.24 mL | 1.19 mL | 2.38 mL |
| 50 mM | 0.05 mL | 0.24 mL | 0.48 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Knapp Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors. J.Pharmacol.Exp.Ther. 1996 PMID: 8667189
- Negus Behavioral effects of the delta-selective opioid agonist SNC80 and related compounds in rhesus monkeys. J.Pharmacol.Exp.Ther. 1998 PMID: 9655881
- Calderon Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective δ agonist (+)-4-[(αR)-α-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-< J.Med.Chem. 1997 PMID: 9057856
Product Specific Notices for SNC 162
For research use only
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