SLIGRL-NH2
Tocris Bioscience, part of Bio-Techne | Catalog # 1468
PAR2-activating peptide
Key Product Details
Description
PAR2-activating peptide
Product Description
SLIGRL-NH2 is an agonist peptide derived from the N-terminus of protease-activated receptor-2 (PAR2). Activates PAR2 (EC50 ~ 5 μM) and facilitates gastrointestinal transit in mice in vivo.Control Peptide also available.
Product Specifications
Molecular Weight
656.82
Formula
C29H56N10O7
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
171436-38-7
PubChem ID
9831050
InChI Key
SGPMJRPYYIJZPC-JYAZKYGWSA-N
SMILES
[H]N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Kawabata In vivo evidence that protease-activated receptors 1 and 2 modulate gastrointestinal transit in the mouse. Br.J.Pharmacol. 2001 PMID: 11498505
- Nystedt Molecular cloning of a potential proteinase activated receptor. Proc.Natl.Acad.Sci.U.S.A. 1994 PMID: 7937743
- Al-Ani Detection of functional receptors for the proteinase-activated-receptor-2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle. Can.J.Physiol.Pharmacol. 1995 PMID: 8564891
Product Specific Notices for SLIGRL-NH2
For research use only
Loading...
Loading...
Loading...