SLIGKV-NH2
Tocris Bioscience, part of Bio-Techne | Catalog # 3010
PAR2 receptor agonist
Key Product Details
Description
PAR2 receptor agonist
Product Description
SLIGKV-NH2 is a protease-activated receptor 2 (PAR2) agonist (Ki = 9.64 μM and IC50 = 10.4 μM). Corresponds to the tethered ligand exposed by trypsin cleavage of PAR-2.Control Peptide also available.
Product Specifications
Molecular Weight
614.78
Formula
C28H54N8O7
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
190383-13-2
PubChem ID
10483914
InChI Key
HOWDUIVVWDUEED-WAUHAFJUSA-N
SMILES
[H]N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Hollenberg and Compton International union of pharmacology XXVIII. Proteinase-activated receptors. Pharmacol.Rev. 2002 PMID: 12037136
- Kanke Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, [3H]2-furoyl-LIGRL-NH2, to human PAR2. Br.J.Pharmacol. 2005 PMID: 15765104
- Bohm Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2. Biochem.J. 1996 PMID: 8615752
Product Specific Notices for SLIGKV-NH2
For research use only
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