SJF 0661
Tocris Bioscience, part of Bio-Techne | Catalog # 7464
Negative control for SJF 0628 (Cat. No. 7463)
Key Product Details
Description
Negative control for SJF 0628 (Cat. No. 7463)
Product Description
SJF 0661 is the negative control for SJF 0628 (Cat. No. 7463). Binds BRAF without inducing degradation.Product Specifications
Molecular Weight
1010.19
Formula
C51H57F2N9O7S2
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(2S,4S)-1-((S)-2-(2-(4-(4-(3-(2,6-Difluoro-3-(propylsulfonamido)benzoyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)piperazin-1-yl)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
CAS Number
2413035-43-3
PubChem ID
146502225
InChI Key
MBCAVOCJJAQHHT-NYNRYUPBSA-N
SMILES
CCCS(=O)(NC1=CC=C(C(C(C2=CNC3=NC=C(C4=CC=C(N5CCN(CC5)CC(N[C@@H](C(C)(C)C)C(N6C[C@H](C[C@H]6C(NCC7=CC=C(C8=C(N=CS8)C)C=C7)=O)O)=O)=O)C=C4)C=C23)=O)=C1F)F)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 101.02 | 100 |
Preparing Stock Solutions
for SJF 0661
The following data is based on the product molecular weight 1010.19
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.99 mL | 4.95 mL | 9.90 mL |
| 5 mM | 0.20 mL | 0.99 mL | 1.98 mL |
| 10 mM | 0.10 mL | 0.49 mL | 0.99 mL |
| 50 mM | 0.02 mL | 0.10 mL | 0.20 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Alabi Mutant-selective degradation by BRAF-targeting PROTACs. Nat.Commun. 2021 PMID: 33568647
Product Specific Notices for SJF 0661
For research use only
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