Scopolamine hydrobromide
Tocris Bioscience, part of Bio-Techne | Catalog # 1414
Non-selective muscarinic antagonist
Key Product Details
Description
Non-selective muscarinic antagonist
Product Description
Scopolamine hydrobromide is a non-selective muscarinic antagonist. Widely used clinically to treat motion sickness.Product Specifications
Molecular Weight
384.27
Formula
C17H21NO4.HBr
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
(α,S)-α-(Hydroxymethyl)benzeneacetic acid (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester hydrobromide
CAS Number
114-49-8
PubChem ID
45073445
InChI Key
WMRMIRRDPBKNMY-ZEECNFPPSA-N
SMILES
O=C([C@@H]([C@]3=CC=CC=C3)CO)O[C@H]1C[C@H]4[C@H](O2)[C@H]2[C@H](N4C)C1.Br
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 38.43 | 100 | |
| DMSO | 19.21 | 50 |
Preparing Stock Solutions
for Scopolamine hydrobromide
The following data is based on the product molecular weight 384.27
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.60 mL | 13.01 mL | 26.02 mL |
| 5 mM | 0.52 mL | 2.60 mL | 5.20 mL |
| 10 mM | 0.26 mL | 1.30 mL | 2.60 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.52 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Nakao Cerebral blood flow responses to somatosensory stimulation are unaffected by scopol. in unanesthetized rat. J.Pharmacol.Exp.Ther. 1999 PMID: 10411611
- Parkes An examination of central actions characteristic of scopolamine: comparison of central and peripheral activity in scopolamine, atr. and some synthetic basic esters. Psychopharmacologia 1965 PMID: 5830966
- Jones and Shannon Effects of scopol. in comparison with apomor. and phencyclidine on prepulse inhibition in rats. Eur.J.Pharmacol. 2000 PMID: 10720641
Product Specific Notices for Scopolamine hydrobromide
For research use only
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