SCH 58261

Tocris Bioscience, part of Bio-Techne | Catalog # 2270

Potent, highly selective A2A antagonist
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Key Product Details

Description

Potent, highly selective A2A antagonist

View all Adenosine A2a Receptor Antagonists »

Product Description

SCH 58261 is a potent and selective A2A adenosine receptor competitive antagonist (Ki = 1.3 nM). Displays 323-, 53- and 100-fold selectivity over A1, A2B and A3 receptors, respectively. Reduces melanoma tumor growth and TGF-β levels in WT and P2X7R-null mice.

Product Specifications

Molecular Weight

345.36

Formula

C18H15N7O

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2-(2-Furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine

CAS Number

160098-96-4

PubChem ID

176408

InChI Key

UTLPKQYUXOEJIL-UHFFFAOYSA-N

SMILES

NC1=NC2=C(C=NN2CCC2=CC=CC=C2)C2=NC(=NN12)C1=CC=CO1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 34.54 100

Preparing Stock Solutions for SCH 58261

The following data is based on the product molecular weight 345.36

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.90 mL 14.48 mL 28.96 mL
5 mM 0.58 mL 2.90 mL 5.79 mL
10 mM 0.29 mL 1.45 mL 2.90 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for SCH 58261

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SCH 58261

For research use only

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