SB 4

Tocris Bioscience, part of Bio-Techne | Catalog # 6881

Potent BMP4 agonist
Catalog #
Availability
Size / Price
Qty
6881/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

Potent BMP4 agonist

View all BMP and Other Activin Receptor Activators »

Product Description

SB 4 is a potent BMP4 agonist (EC50 = 74 nM). Activates canonical BMP signaling and increases SMAD-1/5/9 phosphorylation, with no effect on p-SMAD-2, p-SMAD-3 or p-TAK1. Bypasses noggin-induced inhibition of type I BMP receptors. When used in combination, SB 4 enhances BMP4 signaling and embryonic stem cell differentiation.

Product Specifications

Molecular Weight

320.20

Formula

C14H10BrNOS

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-[[(4-Bromophenyl)methyl]thio]benzoxazole

CAS Number

100874-08-6

PubChem ID

731364

InChI Key

JDVOIBFEFVKUPL-UHFFFAOYSA-N

SMILES

BrC1=CC=C(C=C1)CSC2=NC3=C(C=CC=C3)O2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.02 100
Ethanol 6.4 20

Preparing Stock Solutions for SB 4

The following data is based on the product molecular weight 320.20

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.12 mL 15.62 mL 31.23 mL
5 mM 0.62 mL 3.12 mL 6.25 mL
10 mM 0.31 mL 1.56 mL 3.12 mL
50 mM 0.06 mL 0.31 mL 0.62 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for SB 4

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SB 4

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.