[Sar9,Met(O2)11]-Substance P
Tocris Bioscience, part of Bio-Techne | Catalog # 1178
Potent and selective NK1 agonist
Product Description
[Sar9,Met(O2)11]-Substance P is a potent selective NK1 tachykinin receptor agonist.Product Specifications
Molecular Weight
1393.68
Formula
C64H100N18O15S
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
110880-55-2
PubChem ID
163829
InChI Key
OUPXSLGGCPUZJJ-SARDKLJWSA-N
SMILES
[H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N(C)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCS(C)(=O)=O)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Tousignant 125I-BH[Sar9,Met(O2)11]-SP, a new selective ligand for the NK-1 receptor in the central nervous system. Brain Res. 1990 PMID: 1705465
- King Profile of neuronal excitation following selective activation of the neurokinin-1 receptor in rat deep dorsal horn in vitro. Brain Res. 1997 PMID: 9365015
- Li and Zhao Small sensory neurons in the rat dorsal root ganglia express functional NK-1 tachykinin receptor. Eur.J.Neurosci. 1998 PMID: 9749783
- Cellier Characterisation of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br.J.Pharmacol. 1999 PMID: 10401563
Product Specific Notices for [Sar9,Met(O2)11]-Substance P
For research use only
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