Salbutamol hemisulfate
Tocris Bioscience, part of Bio-Techne | Catalog # 0634
β2-adrenoceptor agonist
Key Product Details
Description
β2-adrenoceptor agonist
Alternative Names
Albuterol
Product Description
Salbutamol hemisulfate is a selective β2-adrenergic agonist with 29-fold higher selectivity for β2 over β1 receptors. Salbutamol elevates fibroblast growth factor 20 (FGF20) in nigrostriatal neurons, and is neuroprotective in a mouse model of Parkinson's disease.Product Specifications
Molecular Weight
288.35
Formula
C13H21NO3.½H2SO4
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol hemisulfate
CAS Number
51022-70-9
PubChem ID
39859
InChI Key
BNPSSFBOAGDEEL-UHFFFAOYSA-N
SMILES
OS(O)(=O)=O.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 28.84 | 100 |
Preparing Stock Solutions
for Salbutamol hemisulfate
The following data is based on the product molecular weight 288.35
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.47 mL | 17.34 mL | 34.68 mL |
| 5 mM | 0.69 mL | 3.47 mL | 6.94 mL |
| 10 mM | 0.35 mL | 1.73 mL | 3.47 mL |
| 50 mM | 0.07 mL | 0.35 mL | 0.69 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Baker The selectivity of beta-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors. Br.J.Pharmacol. 2005 PMID: 15655528
- Fletcher Targeted repositioning identifies drugs that increase fibroblast growth factor 20 production and protect against 6-hydroxydopamine-induced nigral cell loss in rats. Sci.Rep. 2019 PMID: 31171821
- Prior Effects of the enantiomers of R,S-salbutamol on incompletely fused tetanic contractions of slow- and fast-twitch skeletal muscles of the guinea-pig. Br.J.Pharmacol. 1998 PMID: 9504397
- Strosberg and Pietri-Rouxel Function and regulation of the β3-adrenoceptor. TiPS 1996 PMID: 8979772
- January Salmeterol-induced desensitisation, internalization and phosphorylation of the human β2-adrenoceptor. Br.J.Pharmacol. 1998 PMID: 9517390
Product Specific Notices for Salbutamol hemisulfate
For research use only
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