Saclofen
Tocris Bioscience, part of Bio-Techne | Catalog # 0246
Selective GABAB antagonist
Product Description
Saclofen is a selective antagonist at GABAB receptors.Product Specifications
Molecular Weight
249.72
Formula
C9H12ClNO3S
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
(RS)-3-Amino-2-(4-chlorophenyl)propylsulfonic acid
CAS Number
125464-42-8
PubChem ID
122150
InChI Key
JYLNVJYYQQXNEK-UHFFFAOYSA-N
SMILES
NCC(CS(O)(=O)=O)C1=CC=C(Cl)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 2.5 | 10 |
Preparing Stock Solutions
for Saclofen
The following data is based on the product molecular weight 249.72
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.04 mL | 200.22 mL | 400.45 mL |
| 0.5 mM | 8.01 mL | 40.04 mL | 80.09 mL |
| 1 mM | 4.00 mL | 20.02 mL | 40.04 mL |
| 5 mM | 0.80 mL | 4.00 mL | 8.01 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Jane Use of the neonatal rat spinal cord in studies of the GABAB receptor. GABA<sub>B</sub> receptors in Mammalian Function.
- Bowery GABAB receptors and their significance in mammalian pharmacology. TiPS 1989 PMID: 2559518
Product Specific Notices for Saclofen
For research use only
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