S3QEL 2

Name: S3QEL 2
Brand: Tocris Bioscience
SKU: 5735

Tocris Bioscience, part of Bio-Techne | Catalog # 5735

COA / SDS

Suppressor of complex III superoxide production

Discontinued Product

5735 has been discontinued. View all Additional ROS Donor Products products.

Key Product Details

Description:	Suppressor of complex III superoxide production
Chemical Name:	1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity:	≥98% (HPLC)
Molecular Weight:	323.44

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Technical Data
Citations

Biological Activity for S3QEL 2

Suppresses superoxide production by complex III in the mitochondria without affecting normal electron flux or cellular oxidative phosphorylation (IC₅₀ = 1.7 μM). Suppresses HIF-1α accumulation and enhances survival and function of primary pancreatic islets in vitro. Cell permeable.

Technical Data for S3QEL 2

M. Wt	323.44
Formula	C₁₉H₂₅N₅
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	890888-12-7
PubChem ID	17017624
InChi Key	MGIAJZSCNPODRR-UHFFFAOYSA-N
Smiles	CC(C(C)=C1)=CC=C1N2C3=NC=NC(N(CCC)CCC)=C3C=N2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for S3QEL 2

References are publications that support the biological activity of the product.

Orr Suppressors of superoxide production from mitochondrial complex III. Nat.Chem.Biol. 2015 PMID: 26368590

S3QEL 2

Tocris Bioscience, part of Bio-Techne | Catalog # 5735

Key Product Details

Biological Activity for S3QEL 2

Technical Data for S3QEL 2

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for S3QEL 2

Product Documents for S3QEL 2

COA

Certificate of Analysis

SDS

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