(S)-AMPA
Tocris Bioscience, part of Bio-Techne | Catalog # 0254
Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
Key Product Details
Description
Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
Product Description
(S)-AMPA is an active enantiomer of AMPA (EC50 = 3.5 μM).NPEC-caged-(S)-AMPA, Inactive Enantiomer and Racemate also available.
Product Specifications
Molecular Weight
186.17
Formula
C7H10N2O4
Storage
Store at RT
Purity
≥99% (HPLC)
Chemical Name
(S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
CAS Number
83643-88-3
PubChem ID
158397
InChI Key
UUDAMDVQRQNNHZ-YFKPBYRVSA-N
SMILES
[H][C@@](N)(C(O)=O)CC1=C(C)ON=C1O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 9.31 | 50 |
Preparing Stock Solutions
for (S)-AMPA
The following data is based on the product molecular weight 186.17
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 10.74 mL | 53.71 mL | 107.43 mL |
| 2.5 mM | 2.15 mL | 10.74 mL | 21.49 mL |
| 5 mM | 1.07 mL | 5.37 mL | 10.74 mL |
| 25 mM | 0.21 mL | 1.07 mL | 2.15 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Hansen Enzymic resolution and binding to rat brain membranes of the glutamic acid agonist α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid. J.Med.Chem. 1983 PMID: 6133955
- Lauridsen Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity of agonists and antagonists at central glutamic acid receptors. J.Med.Chem. 1985 PMID: 2859375
- Falch Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, photochemistry, and structure-activity relationships. J.Med.Chem. 1998 PMID: 9651156
Product Specific Notices for (S)-AMPA
For research use only
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