RuBi-Nicotine
Tocris Bioscience, part of Bio-Techne | Catalog # 3855
Caged nicotine; rapidly excitable by visible light
Discontinued Product
3855 has been discontinued.
View all Additional Nicotinic Receptor Agonists products.
Key Product Details
Description
Caged nicotine; rapidly excitable by visible light
Product Description
RuBi-Nicotine is a ruthenium-bisbipyridine-caged nicotine, excitable by irradiation with visible light. Undergoes rapid photolysis to release nicotine (< 20 ns); exhibits a high quantum yield. Induces action potential propagation in Retzius neurons of leech ganglia with no detectable toxicity at a concentration of 1 mM.Licensing Information
Sold under licence from Columbia UniversityProduct Specifications
Molecular Weight
808.81
Formula
C40H44Cl2N8Ru
Storage
Store at -20°C
Chemical Name
Bis(2,2'-bipyridine-N,N')bis(S-nicotine-N1) ruthenium(2+) dichloride
CAS Number
1256362-30-7
PubChem ID
90488888
InChI Key
DRYNYXIOLIUZSG-ZPFSJBFKSA-L
SMILES
[Cl-].[Cl-].[Ru++].C1=CN=C(C=C1)C1=CC=CC=N1.C1=CC=C(N=C1)C1=CC=CC=N1.[H][C@]1(CCCN1C)C1=CC=CN=C1.[H][C@]1(CCCN1C)C1=CC=CN=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 40.44 | 50 |
Preparing Stock Solutions
for RuBi-Nicotine
The following data is based on the product molecular weight 808.81
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 2.47 mL | 12.36 mL | 24.73 mL |
| 2.5 mM | 0.49 mL | 2.47 mL | 4.95 mL |
| 5 mM | 0.25 mL | 1.24 mL | 2.47 mL |
| 25 mM | 0.05 mL | 0.25 mL | 0.49 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Filevich A caged nicotine with nanosecond range kinetics and visible light sensitivity. J.Inorg.Biochem. 2010 PMID: 20825994
Product Specific Notices for RuBi-Nicotine
For research use only
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