RuBi GABA trimethylphosphine
Tocris Bioscience, part of Bio-Techne | Catalog # 4709
Caged GABA; inhibits neural activity
Key Product Details
Description
Caged GABA; inhibits neural activity
Alternative Names
RuBi-GABA-PMe3
Product Description
RuBi GABA trimethylphosphine is a modified version of RuBi-GABA (Cat. No. 3400). Suppresses cortical local field potential (LFP) activity in anesthetized mice after activation with a blue laser pulse (473 nm); inhibits neural activity.Licensing Information
Sold under licence from Columbia UniversityProduct Specifications
Molecular Weight
904.56
Formula
C27H33N5O2PRu.PF6.NaPF6
Storage
Store at -20°C
Chemical Name
(bis(2,2'-Bipyridine-N,N')trimethylphosphine)-4-aminobutyric acid ruthenium complex sodium hexafluorophosphate salt
InChI Key
AYYRUPXLUXSCBC-UHFFFAOYSA-N
SMILES
[F-][P+5]([F-])([F-])([F-])([F-])[F-].[F-][P+5]([F-])([F-])([F-])([F-])[F-].CP(C)([Ru+2]12([N]3=CC=CC=C3C4=CC=CC=[N]14)([N]5=CC=CC=C5C6=CC=CC=[N]26)NCCCC([O-])=O)C.[Na+]
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 45.23 | 50 |
Preparing Stock Solutions
for RuBi GABA trimethylphosphine
The following data is based on the product molecular weight 904.56
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 2.21 mL | 11.06 mL | 22.11 mL |
| 2.5 mM | 0.44 mL | 2.21 mL | 4.42 mL |
| 5 mM | 0.22 mL | 1.11 mL | 2.21 mL |
| 25 mM | 0.04 mL | 0.22 mL | 0.44 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Filevich RuBiGABA-2: a hydrophilic caged GABA with long wavelength sensitivity. Photochem.Photobiol.Sci. 2013 PMID: 23674097
- Lopes-dos-Santos In vivo photorelease of GABA in the mouse cortex. Braz.J.Med.Biol.Res. 2011 PMID: 21755263
Product Specific Notices for RuBi GABA trimethylphosphine
For research use only
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