RuBi-4AP
Tocris Bioscience, part of Bio-Techne | Catalog # 3557
Caged 4-aminopyridine; a non-selective KV channel blocker
Discontinued Product
3557 has been discontinued.
View all Voltage-gated Potassium Channel Blockers products.
Key Product Details
Description
Caged 4-aminopyridine; a non-selective KV channel blocker
Alternative Names
Rubi-4-aminopyridine
Product Description
Water soluble ruthenium-bipyridine-triphenylphosphine caged 4-aminopyridine (4-AP). Excited by visible wavelengths and has two-photon uncaging capabilities under physiological conditions. Releases 4-AP (Cat. No. 0940), a voltage-dependent K+ channel blocker.Licensing Information
Sold under licence from Columbia UniversityProduct Specifications
Molecular Weight
672.58
Formula
C30H28Cl2N8Ru
Storage
Store at -20°C
Chemical Name
bis(2,2'-Bipyridine-N,N')bis(4-aminopyridine-N1) ruthenium(2+) dichloride complex
CAS Number
851956-02-0
PubChem ID
11422486
InChI Key
MVEGPXUCOGNVKR-UHFFFAOYSA-L
SMILES
[Cl-].[Cl-].[Ru++].NC1=CC=NC=C1.NC1=CC=NC=C1.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CC=C(N=C1)C1=CC=CC=N1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 20.18 | 30 |
Preparing Stock Solutions
for RuBi-4AP
The following data is based on the product molecular weight 672.58
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.3 mM | 4.96 mL | 24.78 mL | 49.56 mL |
| 1.5 mM | 0.99 mL | 4.96 mL | 9.91 mL |
| 3 mM | 0.50 mL | 2.48 mL | 4.96 mL |
| 15 mM | 0.10 mL | 0.50 mL | 0.99 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Nikolenko Two-photon uncaging of neurochemicals using inorganic metal complexes. Chem.Commun.
- Zayat A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J.Am.Chem.Soc. 2003 PMID: 12537482
Product Specific Notices for RuBi-4AP
For research use only
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