RU 24969 hemisuccinate
Tocris Bioscience, part of Bio-Techne | Catalog # 0912
5-HT1A and 5-HT1B agonist
Product Description
RU 24969 hemisuccinate is a potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.Product Specifications
Molecular Weight
287.34
Formula
C14H16N2O.½C4H6O4
Storage
Store at RT
Purity
≥99% (HPLC)
Chemical Name
5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate
CAS Number
66611-27-6
PubChem ID
3050530
InChI Key
BNYJLRQAWCQJOM-UHFFFAOYSA-N
SMILES
OC(=O)CCC(O)=O.COC1=CC=C2NC=C(C2=C1)C1=CCNCC1.COC1=CC=C2NC=C(C2=C1)C1=CCNCC1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 8.62 | 30 | |
| DMSO | 14.37 | 50 |
Preparing Stock Solutions
for RU 24969 hemisuccinate
The following data is based on the product molecular weight 287.34
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 6.96 mL | 34.80 mL | 69.60 mL |
| 2.5 mM | 1.39 mL | 6.96 mL | 13.92 mL |
| 5 mM | 0.70 mL | 3.48 mL | 6.96 mL |
| 25 mM | 0.14 mL | 0.70 mL | 1.39 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Tomkins and O'Neill Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav. 2000 PMID: 10837852
- Guillaume Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antiDArgic properties. Eur.J.Med.Chem.
- Gudermann Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor. Mol.Pharmacol. 1993 PMID: 8450834
Product Specific Notices for RU 24969 hemisuccinate
For research use only
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