(RS)-MCPG disodium salt
Tocris Bioscience, part of Bio-Techne | Catalog # 3696
Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336)
Key Product Details
Description
Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336)
Product Description
(RS)-MCPG disodium salt is a sodium salt of (RS)-MCPG, a non-selective group I/group II metabotropic glutamate receptor antagonist.S-enantiomer also available.
Product Specifications
Molecular Weight
253.16
Formula
C10H9NNa2O4
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
(RS)-α-Methyl-4-carboxyphenylglycine disodium salt
PubChem ID
90488871
InChI Key
YGOTXTUQJLFNHB-UHFFFAOYSA-L
SMILES
[Na+].[Na+].CC(N)(C([O-])=O)C1=CC=C(C=C1)C([O-])=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 25.32 | 100 |
Preparing Stock Solutions
for (RS)-MCPG disodium salt
The following data is based on the product molecular weight 253.16
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.95 mL | 19.75 mL | 39.50 mL |
| 5 mM | 0.79 mL | 3.95 mL | 7.90 mL |
| 10 mM | 0.40 mL | 1.98 mL | 3.95 mL |
| 50 mM | 0.08 mL | 0.40 mL | 0.79 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Joly Molecular, functional and pharmacological characterization of the metabotropic glutamate receptor Type 5 splice variants: comparison with mGluR1. J.Neurosci. 1995 PMID: 7751958
- Eaton Competitive antagonist at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine (CPG) and (RS)-α-methyl-4-carboxyphenylglycine (MCPG). Eur.J.Pharmacol.Mol.Pharmacol.Sect.
- Collingridge and Watkins Phenylglycine derivatives as metabotropic glutamate receptor antagonists. TiPS 1994 PMID: 7992387
Product Specific Notices for (RS)-MCPG disodium salt
For research use only
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