Ro 04-6790

Tocris Bioscience, part of Bio-Techne | Catalog # 2911

Potent and selective 5-HT6 antagonist
Discontinued Product
2911 has been discontinued. View all 5-HT6 Receptor Antagonists products.

Key Product Details

Description

Potent and selective 5-HT6 antagonist

View all 5-HT6 Receptor Antagonists »

Product Description

Ro 04-6790 is a potent and selective 5-HT6 receptor antagonist (pKi values are 7.26 and 7.35 at rat and human 5-HT6 receptors respectively). Displays no affinity at a range of other receptors (IC50 > 10 μM). Induces stretching behavior in rats in vivo.

Product Specifications

Molecular Weight

308.36

Formula

C12H16N6O2S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

4-Amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]-benzenesulfonamide

CAS Number

202466-68-0

PubChem ID

5312145

InChI Key

JELFWSXQTXRMAJ-UHFFFAOYSA-N

SMILES

NC1=CC=C(S(NC2=NC(NC)=NC(NC)=C2)(=O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 30.84 100

Preparing Stock Solutions for Ro 04-6790

The following data is based on the product molecular weight 308.36

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.24 mL 16.21 mL 32.43 mL
5 mM 0.65 mL 3.24 mL 6.49 mL
10 mM 0.32 mL 1.62 mL 3.24 mL
50 mM 0.06 mL 0.32 mL 0.65 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Ro 04-6790

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ro 04-6790

For research use only

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