RHC 80267

Tocris Bioscience, part of Bio-Techne | Catalog # 1842

Diacylglycerol lipase inhibitor
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Key Product Details

Description

Diacylglycerol lipase inhibitor

Alternative Names

U 57908

View all Lipid Metabolism Inhibitors »

Product Description

RHC 80267 is an inhibitor of diacylglycerol lipase (IC50 values are 1.1 and 4 μM in rat cardiac myocytes and canine platelets respectively). Weakly inhibits phospholipases C and A2. Potentiates acetylcholine evoked relaxation in mesenteric arteries by the inhibition of cholinesterase activity (IC50 = 4 μM).

Product Specifications

Molecular Weight

394.51

Formula

C20H34N4O4

Storage

Store at +4°C

Purity

≥95% (HPLC)

Chemical Name

O,O'-[1,6-Hexanediylbis(iminocarbonyl)]dioxime cyclohexanone

CAS Number

83654-05-1

PubChem ID

5063

InChI Key

RXSVYGIGWRDVQC-UHFFFAOYSA-N

SMILES

O=C(NCCCCCCNC(O/N=C2\CCCCC2)=O)O/N=C1CCCCC/1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.45 100
Ethanol 39.45 100

Preparing Stock Solutions for RHC 80267

The following data is based on the product molecular weight 394.51

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.53 mL 12.67 mL 25.35 mL
5 mM 0.51 mL 2.53 mL 5.07 mL
10 mM 0.25 mL 1.27 mL 2.53 mL
50 mM 0.05 mL 0.25 mL 0.51 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for RHC 80267

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for RHC 80267

For research use only

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