Ramipril

Tocris Bioscience, part of Bio-Techne | Catalog # 5250

Non-peptide, competitive angiotensin-converting enzyme (ACE) inhibitor
Discontinued Product
5250 has been discontinued. View all ACE Inhibitors products.

Key Product Details

Description

Non-peptide, competitive angiotensin-converting enzyme (ACE) inhibitor

View all ACE Inhibitors »

Product Description

Ramipril is a non-peptide, competitive angiotensin converting enzyme (ACE) inhibitor (IC50 = 5 nM). Prodrug which is hydrolyzed in vivo to the active metabolite ramiprilat. Displays protective effects on endothelium against high-glucose induced dysfunction. Exhibits antihypertensive effects.

Product Specifications

Molecular Weight

416.51

Formula

C23H32N2O5

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

(2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid

CAS Number

87333-19-5

PubChem ID

5362129

InChI Key

HDACQVRGBOVJII-JBDAPHQKSA-N

SMILES

[H][C@@]12CCC[C@@]([H])1N(C([C@H](C)N[C@H]([C@@](OCC)=O)CCC3=CC=CC=C3)=O)[C@H]([C@@](O)=O)C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 41.65 100
Ethanol 41.65 100

Preparing Stock Solutions for Ramipril

The following data is based on the product molecular weight 416.51

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.40 mL 12.00 mL 24.01 mL
5 mM 0.48 mL 2.40 mL 4.80 mL
10 mM 0.24 mL 1.20 mL 2.40 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Ramipril

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ramipril

For research use only

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