Quinelorane hydrochloride

Name: Quinelorane hydrochloride
Brand: Tocris Bioscience
SKU: 1519

Tocris Bioscience, part of Bio-Techne | Catalog # 1519

Citations (3)

COA / SDS

D2 and D3 agonist

Discontinued Product

1519 has been discontinued. View all Non-selective Dopamine Receptor Agonists products.

Key Product Details

Description:	D₂ and D₃ agonist
Alternative Names:	LY 163502
Chemical Name:	(5aR,9aR)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	319.27

View Full Technical Details for Quinelorane hydrochloride

Technical Data
Citations

Biological Activity for Quinelorane hydrochloride

Quinelorane hydrochloride is a dopamine D₂ and D₃ receptor agonist; K_i values are 5.7 and 3.4 nM respectively.

Licensing Information

Sold with the permission of Eli Lilly and Company

Technical Data for Quinelorane hydrochloride

M. Wt	319.27
Formula	C₁₄H₂₂N₄.2HCl
Storage	Desiccate at RT
Purity	≥99% (HPLC)
CAS Number	97548-97-5
PubChem ID	68728
InChi Key	WDEMLQIGYYLRRX-OWVUFADGSA-N
Smiles	[H][C@]23[C@@](CCCN3CCC)([H])CC1=NC(N)=NC=C1C2.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Quinelorane hydrochloride

References are publications that support the biological activity of the product.

Eaton Effects of the selective DArgic D₂ agonist quinelorane on the activity of DArgic and noradrenergic neurons projecting to the diencephalon of the rat. J.Pharmacol.Exp.Ther. 1994 PMID: 7906734
Flietstra and Levant Comparison of D₂ and D₃ DA receptor affinity of DArgic compounds in the rat brain. Life Sci. 1998 PMID: 9600324
Foreman Preclinical studies on quinelorane, a potent and highly selective D₂-DArgic agonist. J.Pharmacol.Exp.Ther. 1989 PMID: 2526214