PSB 0739

Name: PSB 0739
Brand: Tocris Bioscience
SKU: 3983
Rating: 4 (2 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 3983

(2)

Citations (75)

COA / SDS

Highly potent P2Y12 antagonist

Key Product Details

Description:	Highly potent P2Y₁₂ antagonist
Chemical Name:	1-Amino-9,10-dihydro-9,10-dioxo-4-[[4-(phenylamino)-3-sulfophenyl]amino]-2-anthracenesulfonic acid sodium salt
Purity:	≥95% (HPLC)
Molecular Weight:	609.54

View Full Technical Details for PSB 0739

Technical Data
Citations / Reviews (2)

Biological Activity for PSB 0739

PSB 0739 is a highly potent P2Y₁₂ receptor antagonist (K_i = 24.9 nM). Unlike clopidogrel (Cat. No. 2490), does not require bioactivation.

Licensing Information

Sold with the permission of the University of Bonn.

Technical Data for PSB 0739

M. Wt	609.54
Formula	C₂₆H₁₇N₃Na₂O₈S₂
Storage	Desiccate at RT
Purity	≥95% (HPLC)
CAS Number	1052087-90-7
PubChem ID	44583582
InChi Key	QBLLYXXXOJUNCV-UHFFFAOYSA-L
Smiles	[Na+].[Na+].NC1=C(C=C(NC2=CC(=C(NC3=CC=CC=C3)C=C2)S([O-])(=O)=O)C2=C1C(=O)C1=CC=CC=C1C2=O)S([O-])(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for PSB 0739

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	15.24	25

Preparing Stock Solutions for PSB 0739

The following data is based on the product molecular weight 609.54.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	6.56 mL	32.81 mL	65.62 mL
1.25 mM	1.31 mL	6.56 mL	13.12 mL
2.5 mM	0.66 mL	3.28 mL	6.56 mL
12.5 mM	0.13 mL	0.66 mL	1.31 mL

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References for PSB 0739

References are publications that support the biological activity of the product.

Baqi High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y₁₂ receptors. J.Med.Chem. 2009 PMID: 19463000
Felix Development of a comprehensive set of P2 receptor pharmacological research compounds. Purinerg.Sig. 2011 PMID: 22052555
Hoffmann Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y₁₂ receptor. J.Pharmacol.Exp.Ther. 2009 PMID: 19690189