PRX 07034
Tocris Bioscience, part of Bio-Techne | Catalog # 6748
Potent and selective 5-HT6 antagonist
Key Product Details
Description
Potent and selective 5-HT6 antagonist
Product Description
PRX 07034 is a potent and selective 5-HT6 receptor antagonist (IC50 = 19 nM, Ki = 4 - 8 nM). Enhances working memory in rats.Product Specifications
Molecular Weight
490.44
Formula
C21H28ClN3O4S.HCl
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-(1-(5-Chloro-2,3-dimethoxyphenyl)ethyl)-2-(methylsulfonyl)-5-(piperazin-1-yl)aniline hydrochloride
CAS Number
903580-39-2
PubChem ID
23653584
InChI Key
PILCQJJJAFRKHO-UHFFFAOYSA-N
SMILES
ClC1=CC(C(NC2=C(S(C)(=O)=O)C=CC(N3CCNCC3)=C2)C)=C(OC)C(OC)=C1.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 9.81 | 20 with gentle warming | |
| DMSO | 49.04 | 100 |
Preparing Stock Solutions
for PRX 07034
The following data is based on the product molecular weight 490.44
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.04 mL | 10.19 mL | 20.39 mL |
| 5 mM | 0.41 mL | 2.04 mL | 4.08 mL |
| 10 mM | 0.20 mL | 1.02 mL | 2.04 mL |
| 50 mM | 0.04 mL | 0.20 mL | 0.41 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Mohler The effects of PRX-07034, a novel 5-HT6 antagonist, on cognitive flexibility and working memory in rats. Psychopharmacology (Berl). 2012 PMID: 21989804
Product Specific Notices for PRX 07034
For research use only
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