[Pro³]-GIP (Rat)

Name: [Pro 3 ]-GIP (Rat)
Brand: Tocris Bioscience
SKU: 5837

Tocris Bioscience, part of Bio-Techne | Catalog # 5837

COA / SDS

High affinity rat GIP partial agonist

Discontinued Product

5837 has been discontinued. View all GIP Receptor Agonists products.

Key Product Details

Description:	High affinity rat GIP partial agonist
Molecular Weight:	4970.63

View Full Technical Details for [Pro³]-GIP (Rat)

Technical Data
Citations

Biological Activity for [Pro³]-GIP (Rat)

[Pro³]-GIP (Rat) is a high affinity rat GIP receptor partial agonist (K_d = 13 nM). Increases cAMP accumulation in COS-7 cells transfected with rat GIP receptor, while also acting as a competitive antagonist of GIP.

Technical Data for [Pro³]-GIP (Rat)

M. Wt	4970.63
Formula	C₂₂₆H₃₄₃N₆₁O₆₄S
Single Letter Sequence	YAPGTFISDYSIAMDKIRQQDFVNWLLAQKGKKNDWKHNLTQ
Storage	Store at -20°C
PubChem ID	121513896
InChi Key	MAEZQGLUYPOMQT-DYJGCSTISA-N
Smiles	[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for [Pro³]-GIP (Rat)

References are publications that support the biological activity of the product.

Sparre-Ulrich Species-specific action of (Pro³)GIP - a full agonist at human GIP receptors, but a partial agonist and competitive antagonist at rat and mouse GIP receptors. Br.J.Pharmacol. 2016 PMID: 26359804

[Pro³]-GIP (Rat)

Tocris Bioscience, part of Bio-Techne | Catalog # 5837

Key Product Details

Biological Activity for [Pro³]-GIP (Rat)

Technical Data for [Pro³]-GIP (Rat)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [Pro³]-GIP (Rat)

Product Documents for [Pro³]-GIP (Rat)

COA

Certificate of Analysis

SDS

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[Pro3]-GIP (Rat)

Tocris Bioscience, part of Bio-Techne | Catalog # 5837

Key Product Details

Biological Activity for [Pro3]-GIP (Rat)

Technical Data for [Pro3]-GIP (Rat)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [Pro3]-GIP (Rat)

Product Documents for [Pro3]-GIP (Rat)

COA

Certificate of Analysis

SDS

[Pro³]-GIP (Rat)

Biological Activity for [Pro³]-GIP (Rat)

Technical Data for [Pro³]-GIP (Rat)

References for [Pro³]-GIP (Rat)

Product Documents for [Pro³]-GIP (Rat)