Pomalidomide 4'-alkylC5-acid
Tocris Bioscience, part of Bio-Techne | Catalog # 6682
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
Key Product Details
Description
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
Alternative Names
Pomalidomide - linker 3
Product Description
Pomalidomide 4'-alkylC5-acid is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC5 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.This product has been recently renamed. The previous name for this product was Pomalidomide - linker 3
Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
387.39
Formula
C19H21N3O6
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid
CAS Number
2225940-49-6
PubChem ID
134501173
InChI Key
FOHDGJCYBZWKCE-UHFFFAOYSA-N
SMILES
OC(CCCCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Molarity Calculator
Dilution Calculator
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Background References
References are publications that support the biological activity of the product.
- Remillard Degradation of the BAF complex factor BRD9 by heterobifunctional ligands. Angew.Chem.Int.Ed.Engl. 2017 PMID: 28418626
Product Specific Notices for Pomalidomide 4'-alkylC5-acid
For research use only
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