(+)-Clopidogrel hydrogen sulfate

Tocris Bioscience, part of Bio-Techne | Catalog # 1820

Selective P2Y12 antagonist
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Key Product Details

Description

Selective P2Y12 antagonist

Alternative Names

Plavix

View all P2Y Receptor Antagonists »

Product Description

(+)-Clopidogrel hydrogen sulfate is a selective, high affinity P2Y12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity. Active enantiomer of (±)-clopidogrel hydrochloride (Cat. No. 2490). Requires bioactivation.

Product Specifications

Molecular Weight

419.90

Formula

C16H16ClNO2S.H2SO4

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogen sulfate

CAS Number

120202-66-6

PubChem ID

115366

InChI Key

FDEODCTUSIWGLK-RSAXXLAASA-N

SMILES

OS(O)(=O)=O.COC(=O)[C@@H](N1CCC2=C(C1)C=CS2)C1=CC=CC=C1Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 41.99 100
DMSO 41.99 100

Preparing Stock Solutions for (+)-Clopidogrel hydrogen sulfate

The following data is based on the product molecular weight 419.90

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.38 mL 11.91 mL 23.82 mL
5 mM 0.48 mL 2.38 mL 4.76 mL
10 mM 0.24 mL 1.19 mL 2.38 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

  • Savi and Herbert Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas.
  • Reist Very low chiral inversion of clopid. in rats: a pharmacokinetic and mechanistic investigation. Drug Metab.Disp.
  • Savi P2Y12, a new platelet ADP receptor, target of clopid. Biochem.Biophys.Res.Comm.
  • Kugelgen Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 2006 PMID: 16257449

Product Documents for (+)-Clopidogrel hydrogen sulfate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (+)-Clopidogrel hydrogen sulfate

For research use only

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