PluriSln 1
Tocris Bioscience, part of Bio-Techne | Catalog # 4847
SCD-1 inhibitor
Key Product Details
Description
SCD-1 inhibitor
Alternative Names
NSC 14613
Product Description
PluriSln 1 is a stearoyl-CoA desaturase 1 (SCD1) inhibitor. Used to selectively eliminate undifferentiated human pluripotent stem cells (hPSCs) from culture; induces ER stress, attenuates protein synthesis and induces apoptosis in hPSCs. Prevents teratoma formation in immunocompromised mice.Product Specifications
Molecular Weight
213.24
Formula
C12H11N3O
Storage
Store at +4°C
Purity
≥99% (HPLC)
Chemical Name
4-Pyridinecarboxylic acid 2-phenylhydrazide
CAS Number
91396-88-2
PubChem ID
225362
InChI Key
HUDWXDLBWRHCKO-UHFFFAOYSA-N
SMILES
O=C(NNC2=CC=CC=C2)C1=CC=NC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 21.32 | 100 | |
| Ethanol | 21.32 | 100 |
Preparing Stock Solutions
for PluriSln 1
The following data is based on the product molecular weight 213.24
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.69 mL | 23.45 mL | 46.90 mL |
| 5 mM | 0.94 mL | 4.69 mL | 9.38 mL |
| 10 mM | 0.47 mL | 2.34 mL | 4.69 mL |
| 50 mM | 0.09 mL | 0.47 mL | 0.94 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Ben-David Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen. Cell Stem Cell 2013 PMID: 23318055
Product Specific Notices for PluriSln 1
For research use only
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