Phalloidin

Name: Phalloidin
Brand: Tocris Bioscience
SKU: 4535

Tocris Bioscience, part of Bio-Techne | Catalog # 4535

Citations (21)

COA / SDS

Promotes actin polymerization

Key Product Details

Description:	Promotes actin polymerization
Purity:	≥90% (HPLC)
Molecular Weight:	788.87

View Full Technical Details for Phalloidin

Technical Data
Citations

Biological Activity for Phalloidin

Phalloidin is a promotes actin polymerization. Decreases dissociation rate constant for actin subunits from filament ends; lowers critical concentration for polymerization.

Technical Data for Phalloidin

M. Wt	788.87
Formula	C₃₅H₄₈N₈O₁₁S
Single Letter Sequence	ATCXAWL (Modifications: Cyclic Cys-3-Trp-6, X=Hyp, D-Thr-2)
Storage	Store at -20°C
Purity	≥90% (HPLC)
CAS Number	17466-45-4
PubChem ID	90488951
InChi Key	KPKZJLCSROULON-RCGKFKHASA-N
Smiles	O=C([C@H](N5)CSC(NC3=C2C=CC=C3)=C2C[C@@H](C(N[C@@H](C[C@](O)(C)CO)C(NC(C(N[C@H]([C@H](C)O)C5=O)=O)C)=O)=O)NC([C@@H](N[C@]4=O)C)=O)N1[C@H]4C[C@@H](O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Phalloidin

Solubility

Soluble to 1mg/ml in water

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References for Phalloidin

References are publications that support the biological activity of the product.

Wehland Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth. Proc.Natl.Acad.Sci.USA 1977 PMID: 341163
Cooper Effects of cytochalasin and phalloidin on actin. J.Cell Biol. 1987 PMID: 3312229
Coluccio and Tilney Phalloidin enhances actin assembly by preventing monomer dissociation. J.Cell Biol. 1984 PMID: 6746738
Diensthuber Phalloidin perturbs the interaction of human non-muscle myosin isoforms 2A and 2C1 with F-actin. FEBS Lett. 2011 PMID: 21295570