PD 168077 maleate

Tocris Bioscience, part of Bio-Techne | Catalog # 1065

High affinity, selective D4 agonist
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Key Product Details

Description

High affinity, selective D4 agonist

View all Dopamine D4 Receptor Agonists »

Product Description

PD 168077 maleate is a potent D4 dopamine receptor agonist (Ki = 8.7 nM) with > 400-fold selectivity over D2 and > 300-fold selectivity versus D3 subtypes respectively. Induces synaptic translocation of CaMK II to postsynaptic sites in cultured prefrontal cortical neurons. Centrally active in vivo.

Product Specifications

Molecular Weight

450.49

Formula

C20H22N4O.C4H4O4

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-[[4-(2-Cyanophenyl)-1-piperazinyl]methyl]-3-methylbenzamide maleate

CAS Number

630117-19-0

PubChem ID

11957665

InChI Key

NAEUGRPISCANHO-BTJKTKAUSA-N

SMILES

OC(=O)\C=C/C(O)=O.CC1=CC(=CC=C1)C(=O)NCN1CCN(CC1)C1=C(C=CC=C1)C#N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 45.05 100

Preparing Stock Solutions for PD 168077 maleate

The following data is based on the product molecular weight 450.49

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.22 mL 11.10 mL 22.20 mL
5 mM 0.44 mL 2.22 mL 4.44 mL
10 mM 0.22 mL 1.11 mL 2.22 mL
50 mM 0.04 mL 0.22 mL 0.44 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for PD 168077 maleate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PD 168077 maleate

For research use only

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