PD 166793

Tocris Bioscience, part of Bio-Techne | Catalog # 2520

Broad spectrum MMP inhibitor
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Key Product Details

Description

Broad spectrum MMP inhibitor

View all Matrix Metalloprotease (MMP) Inhibitors »

Product Description

PD 166793 is a broad spectrum MMP inhibitor. Displays high affinity for MMP-2, -3 and -13 (IC50 values are 4, 7 and 8 nM respectively) and exhibits > 750-fold selectivity over MMP-1, -7 and -9. Attenuates left ventricular remodelling and dysfunction in rat model of heart failure.

Product Specifications

Molecular Weight

412.30

Formula

C17H18BrNO4S

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-[(4'-Bromo[1,1'-biphenyl]-4-yl)sulfonyl]-L-valine

CAS Number

199850-67-4

PubChem ID

9887870

InChI Key

GJOCABIDMCKCEG-INIZCTEOSA-N

SMILES

BrC1=CC=C(C2=CC=C(S(N[C@@H]([C@H](C)C)C(O)=O)(=O)=O)C=C2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 41.23 100
Ethanol 41.23 100

Preparing Stock Solutions for PD 166793

The following data is based on the product molecular weight 412.30

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.43 mL 12.13 mL 24.25 mL
5 mM 0.49 mL 2.43 mL 4.85 mL
10 mM 0.24 mL 1.21 mL 2.43 mL
50 mM 0.05 mL 0.24 mL 0.49 mL

Calculators

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Reconstitution Calculator

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Product Documents for PD 166793

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PD 166793

For research use only

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