Palmitoylethanolamide

Tocris Bioscience, part of Bio-Techne | Catalog # 0879

Selective GPR55 agonist. FAAH and PAA substrate
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Key Product Details

Description

Selective GPR55 agonist. FAAH and PAA substrate

Alternative Names

PEA

View all GPR55 Receptor Agonists »

Product Description

Palmitoylethanolamide is an endogenous lipid that acts as a selective GPR55 agonist (EC50 values are 4, 19 800 and > 30 000 nM at GPR55, CB2 and CB1 receptors respectively). Substrate for fatty acid amide hydrolase (FAAH) and PEA-preferring acid amidase (PAA) and exhibits antinociceptive and anticonvulsant in vivo. Directly activates PPARα (EC50 = 3 μM) producing robust anti-inflammatory actions.

Product Specifications

Molecular Weight

299.50

Formula

C18H37NO2

Storage

Store at RT

Chemical Name

N-(2-Hydroxyethyl)hexadecanamide

CAS Number

544-31-0

PubChem ID

4671

InChI Key

HXYVTAGFYLMHSO-UHFFFAOYSA-N

SMILES

O=C(CCCCCCCCCCCCCCC)NCCO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 5.99 20
Ethanol 7.49 25

Preparing Stock Solutions for Palmitoylethanolamide

The following data is based on the product molecular weight 299.50

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 13.36 mL 66.78 mL 133.56 mL
1.25 mM 2.67 mL 13.36 mL 26.71 mL
2.5 mM 1.34 mL 6.68 mL 13.36 mL
12.5 mM 0.27 mL 1.34 mL 2.67 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Palmitoylethanolamide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Palmitoylethanolamide

For research use only

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