O-Phospho-L-serine

Name: O -Phospho-L-serine
Brand: Tocris Bioscience
SKU: 0238

Tocris Bioscience, part of Bio-Techne | Catalog # 0238

Citations (1)

COA / SDS

Group III mGlu agonist

Discontinued Product

0238 has been discontinued. View all Group III mGluR Agonists products.

Key Product Details

Description:	Group III mGlu agonist
Alternative Names:	L-SOP
Chemical Name:	L-Serine-O-phosphate
Molecular Weight:	185.07

View Full Technical Details for O-Phospho-L-serine

Technical Data
Citations

Biological Activity for O-Phospho-L-serine

O-Phospho-L-serine is a group III metabotropic glutamate receptor agonist; analog of L-AP4 (Cat. No. 0103). Neuroprotective against excitotoxicity in cortical cell cultures. Inhibits proliferation and enhances neuronal differentiation in progenitor cells.

Technical Data for O-Phospho-L-serine

M. Wt	185.07
Formula	C₃H₈NO₆P
Storage	Store at RT
CAS Number	407-41-0
PubChem ID	68841
InChi Key	BZQFBWGGLXLEPQ-REOHCLBHSA-N
Smiles	[H][C@@](COP(O)(O)=O)(N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for O-Phospho-L-serine

References are publications that support the biological activity of the product.

Park Expanding the genetic code of Escherichia coli with phosphoserine. Science 2011 PMID: 21868676
Yang A chemical biology route to site-specific authentic protein modifications. Science 2016 PMID: 27708052
Saxe A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation. Chem.Biol. 2007 PMID: 17884634
Thoreson and Ulphani Pharmacology of selective and non-selective metabotropic glutamate receptor agonists at L-AP4 receptors in ON bipolar cells. Brain Res. 1995 PMID: 7796182
Eriksen and Thomsen [³H]-L-2-amino-4-phosphonobutyrate labels a metabotropic glutamate receptor, mGluR4a. Br.J.Pharmacol. 1995 PMID: 8719808
Bruno Activation of group III metabotropic glutamate receptors is neuroprotective in cortical cultures. Eur.J.Pharmacol. 1996 PMID: 8880068

O-Phospho-L-serine

Tocris Bioscience, part of Bio-Techne | Catalog # 0238

Key Product Details

Biological Activity for O-Phospho-L-serine

Technical Data for O-Phospho-L-serine

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for O-Phospho-L-serine

Product Documents for O-Phospho-L-serine

COA

Certificate of Analysis

SDS

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