NQDI 1

Name: NQDI 1
Brand: Tocris Bioscience
SKU: 4429

Tocris Bioscience, part of Bio-Techne | Catalog # 4429

Citations (4)

COA / SDS

ASK1 inhibitor

Discontinued Product

4429 has been discontinued. View all ASK1 Inhibitors products.

Key Product Details

Description:	ASK1 inhibitor
Chemical Name:	2,7-Dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid ethyl ester
Purity:	≥99% (HPLC)
Molecular Weight:	319.31

View Full Technical Details for NQDI 1

Technical Data
Citations

Biological Activity for NQDI 1

NQDI 1 is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC₅₀ = 3 μM, K_i = 500 nM).

Technical Data for NQDI 1

M. Wt	319.31
Formula	C₁₉H₁₃NO₄
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	175026-96-7
PubChem ID	5522952
InChi Key	UFJGFNHRMPMALC-UHFFFAOYSA-N
Smiles	O=C2NC1=CC=CC4=C1C(C3=CC=CC=C3C4=O)=C2C(OCC)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for NQDI 1

References are publications that support the biological activity of the product.

Volynets Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as inhibitors of apoptosis signal-regulating kinase 1 (ASK1). J.Med.Chem. 2011 PMID: 21449566
Bu Synthesis and cytotoxic activity of 7-oxo-7H-dibenz[f,ij]isoquinoline and 7-oxo-7H-benzo[e]perimidine derivatives. J.Med.Chem. 2001 PMID: 11384245

NQDI 1

Tocris Bioscience, part of Bio-Techne | Catalog # 4429

Key Product Details

Biological Activity for NQDI 1

Technical Data for NQDI 1

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for NQDI 1

Product Documents for NQDI 1

COA

Certificate of Analysis

SDS

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