ML 213

Tocris Bioscience, part of Bio-Techne | Catalog # 4519

KV7.2 and KV7.4 channel opener
Catalog #
Availability
Size / Price
Qty
4519/10
4519/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

KV7.2 and KV7.4 channel opener

View all Voltage-gated Potassium Channel Activators »

Product Description

ML 213 is a selective KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener (EC50 values are 230 and 510 nM for KV7.2 and KV7.4 respectively). Displays > 80-fold selectivity against KV7.1, KV7.3 and KV7.5 in a thallium-based fluorescence assay. Hyperpolarizes resting membrane potential in an in vitro spinal cord preparation.

Product Specifications

Molecular Weight

257.37

Formula

C17H23NO

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

N-(2,4,6-Trimethylphenyl)-bicyclo[2.2.1]heptane-2-carboxamide

CAS Number

489402-47-3

PubChem ID

3111211

InChI Key

SIQGKPGBLYKQBB-UHFFFAOYSA-N

SMILES

O=C(NC3=C(C)C=C(C)C=C3C)C1CC2CCC1C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 12.87 50
Ethanol 12.87 50

Preparing Stock Solutions for ML 213

The following data is based on the product molecular weight 257.37

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 7.77 mL 38.85 mL 77.71 mL
2.5 mM 1.55 mL 7.77 mL 15.54 mL
5 mM 0.78 mL 3.89 mL 7.77 mL
25 mM 0.16 mL 0.78 mL 1.55 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Product Documents for ML 213

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ML 213

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.