Minoxidil

Name: Minoxidil
Brand: Tocris Bioscience
SKU: 0583
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 0583

(1)

Citations (10)

COA / SDS

Kir6 channel (KATP) opener

Key Product Details

Description:	K_ir6 channel (K_ATP) opener
Chemical Name:	6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide
Purity:	≥98% (HPLC)
Molecular Weight:	209.25

View Full Technical Details for Minoxidil

Technical Data
Citations / Reviews (1)

Biological Activity for Minoxidil

Minoxidil is an antihypertensive. Antialopecia agent. K_ir6 channel (K_ATP) activator.

Compound Libraries for Minoxidil

Minoxidil is also offered as part of the Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.

Technical Data for Minoxidil

M. Wt	209.25
Formula	C₉H₁₅N₅O
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	38304-91-5
PubChem ID	4201
InChi Key	ZIMGGGWCDYVHOY-UHFFFAOYSA-N
Smiles	NC1=CC(=NC(N)=[N+]1[O-])N1CCCCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Minoxidil

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	ethanol	5.23	25
	DMSO	5.23	25 with gentle warming

Preparing Stock Solutions for Minoxidil

The following data is based on the product molecular weight 209.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	19.12 mL	95.58 mL	191.16 mL
1.25 mM	3.82 mL	19.12 mL	38.23 mL
2.5 mM	1.91 mL	9.56 mL	19.12 mL
12.5 mM	0.38 mL	1.91 mL	3.82 mL

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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References for Minoxidil

References are publications that support the biological activity of the product.

Meisheri Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil. Biochem.Pharmacol. 1993 PMID: 8435087
Tsoporis Effects of the arterial vasodilator minoxidil on cardiovascular structure and sympathetic activity in spontaneously hypertensive rats. J.Hypertens. 1993 PMID: 8133016
Lachgar Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells. Br.J.Dermatol. 1998 PMID: 9580790