Methylmalonate

Tocris Bioscience, part of Bio-Techne | Catalog # 4979

Succinate dehydrogenase inhibitor
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Key Product Details

Description

Succinate dehydrogenase inhibitor

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Product Description

Methylmalonate is an intracellularly produced malonate, a reversible succinate dehydrogenase inhibitor used to generate Huntington's disease models. Induces apoptotic cell death in striatal neurons.

Product Specifications

Molecular Weight

118.09

Formula

C4H6O4

Storage

Store at RT

Purity

≥98%

Chemical Name

2-Methylpropanedioic acid

CAS Number

516-05-2

PubChem ID

487

InChI Key

ZIYVHBGGAOATLY-UHFFFAOYSA-N

SMILES

OC(C(C)C(O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1.1eq. NaOH 11.81 100
DMSO 11.81 100

Preparing Stock Solutions for Methylmalonate

The following data is based on the product molecular weight 118.09

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 8.47 mL 42.34 mL 84.68 mL
5 mM 1.69 mL 8.47 mL 16.94 mL
10 mM 0.85 mL 4.23 mL 8.47 mL
50 mM 0.17 mL 0.85 mL 1.69 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Methylmalonate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Methylmalonate

For research use only

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