MDL 72832 hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0412
Potent 5-HT1A ligand
Discontinued Product
0412 has been discontinued.
View all 5-HT1A Receptor Ligands products.
Product Description
MDL 72832 hydrochloride is a potent ligand at 5-HT1A receptors, with mixed agonist and antagonist properties. An agonist at post-synaptic 5-HT1A receptors.Product Specifications
Molecular Weight
422.95
Formula
C22H30N2O4.HCl
Storage
Store at RT
Purity
≥99% (HPLC)
Chemical Name
8-[4-(1,4-Benzodioxan-2-ylmethylamino)butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride
CAS Number
113777-40-5
PubChem ID
45073438
InChI Key
GQGDGISNRPBRSG-UHFFFAOYSA-N
SMILES
Cl.O=C1CC2(CCCC2)CC(=O)N1CCCCNCC1COC2=CC=CC=C2O1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 5 |
Preparing Stock Solutions
for MDL 72832 hydrochloride
The following data is based on the product molecular weight 422.95
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.05 mM | 47.29 mL | 236.43 mL | 472.87 mL |
| 0.25 mM | 9.46 mL | 47.29 mL | 94.57 mL |
| 0.5 mM | 4.73 mL | 23.64 mL | 47.29 mL |
| 2.5 mM | 0.95 mL | 4.73 mL | 9.46 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Mir MDL 72832: a potent and stereoselective ligand at central and peripheral 5-HT1A receptors. Eur.J.Pharmacol. 1988 PMID: 2840295
- Millan Induction of hypothermia as a model of 5-hydroxytryptamine1A receptor-mediated activity in the rat - a pharmacological characterization of the actions of novel agonists and antagonists. J.Pharmacol.Exp.Ther. 1993 PMID: 8450471
Product Specific Notices for MDL 72832 hydrochloride
For research use only
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