MCL 0020

Name: MCL 0020
Brand: Tocris Bioscience
SKU: 3438

Tocris Bioscience, part of Bio-Techne | Catalog # 3438

COA / SDS

Selective MC4 receptor antagonist

Discontinued Product

3438 has been discontinued. View all Melanocortin Receptor Antagonists products.

Key Product Details

Description:	Selective MC₄ receptor antagonist
Molecular Weight:	609.73

View Full Technical Details for MCL 0020

Technical Data
Citations

Biological Activity for MCL 0020

MCL 0020 is a potent and selective melanocortin MC₄ receptor antagonist (IC₅₀ values are 11.63, 1115 and > 10 000 nM at MC₄, MC₃ and MC₁ receptors respectively). Significantly reverses stress-induced anorexia but has no effect on food intake in free-feeding rats. Exhibits anxiolytic-like activity in vivo.

Technical Data for MCL 0020

M. Wt	609.73
Formula	C₃₄H₃₉N₇O₄
Single Letter Sequence	XRX (Modifications: X-1 = Ac-D-2-Nal, X-3 = 2-Nal & C-terminal amide)
Storage	Store at -20°C
CAS Number	475498-26-1
PubChem ID	9938789
InChi Key	FJFLYSMWSRRMRO-FRXPANAUSA-N
Smiles	CC(=O)N[C@H](CC1=CC2=CC=CC=C2C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](CC1=CC2=CC=CC=C2C=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for MCL 0020

References are publications that support the biological activity of the product.

Chaki Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents. Eur.J.Pharmacol. 2003 PMID: 12909200

MCL 0020

Tocris Bioscience, part of Bio-Techne | Catalog # 3438

Key Product Details

Biological Activity for MCL 0020

Technical Data for MCL 0020

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for MCL 0020

Product Documents for MCL 0020

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

Stay Connected