M871

Tocris Bioscience, part of Bio-Techne | Catalog # 2698

COA / SDS

Selective GAL2 antagonist

Key Product Details

Description:	Selective GAL₂ antagonist
Alternative Names:	Galanin-(2-13)-Glu-His-(Pro)₃-(Ala-Leu)₂-Ala-amide
Purity:	≥95% (HPLC)
Molecular Weight:	2287.64

View Full Technical Details for M871

Technical Data
Citations

Biological Activity for M871

M871 is a selective galanin GAL₂ receptor antagonist (K_i values are 13.1 and 420 nM for GAL₂ and GAL₁ receptors respectively). Blocks the pro-nociceptive effect of GAL₂ receptor agonists.

Technical Data for M871

M. Wt	2287.64
Formula	C₁₀₈H₁₆₃N₂₇O₂₈
Single Letter Sequence	WTLNSAGYLLGPEHPPPALALA (Modification: Ala-22 = C-terminal amide)
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	908844-75-7
PubChem ID	90477989
InChi Key	BHKXASDHGWBINL-ZEHYZEGSSA-N
Smiles	[H]N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for M871

Solubility

Soluble to 1mg/ml in water

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for M871

References are publications that support the biological activity of the product.

Sollenburg M871 - a novel peptide antagonist selectively recognizing the galanin receptor type 2. Int.J.Pept.Res.Ther.
Jimenez-Andrade Activation of peripheral galanin receptors: differential effects on nociception. Pharmacol.Biochem.Behav. 2006 PMID: 16996122