m-3M3FBS

Name: m -3M3FBS
Brand: Tocris Bioscience
SKU: 1941

Tocris Bioscience, part of Bio-Techne | Catalog # 1941

Citations (45)

COA / SDS

Phospholipase C activator

Key Product Details

Description:	Phospholipase C activator
Chemical Name:	2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
Purity:	≥98% (HPLC)
Molecular Weight:	343.36

View Full Technical Details for m-3M3FBS

Technical Data
Citations

Biological Activity for m-3M3FBS

m-3M3FBS is an activator of phospholipase C (PLC). Stimulates superoxide generation, Ca²⁺ release and inositol phosphate formation in a variety of cell types. Also inhibits growth of the leukemic cell lines U937 and THP-1.

Negative Control also available.

Compound Libraries for m-3M3FBS

m-3M3FBS is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for m-3M3FBS

M. Wt	343.36
Formula	C₁₆H₁₆F₃NO₂S
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	200933-14-8
PubChem ID	761523
InChi Key	ZIIUUSVHCHPIQD-UHFFFAOYSA-N
Smiles	CC1=CC(C)=C(C(C)=C1)S(=O)(=O)NC1=CC=CC(=C1)C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for m-3M3FBS

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	ethanol	34.34	100
	DMSO	34.34	100

Preparing Stock Solutions for m-3M3FBS

The following data is based on the product molecular weight 343.36.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.91 mL	14.56 mL	29.12 mL
5 mM	0.58 mL	2.91 mL	5.82 mL
10 mM	0.29 mL	1.46 mL	2.91 mL
50 mM	0.06 mL	0.29 mL	0.58 mL

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Reconstitution Calculator

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References for m-3M3FBS

References are publications that support the biological activity of the product.

Krjukova Phospholipase C activator m-3M3FBS affects Ca²⁺ homeostasis independently of phospholipase C activation. Br.J.Pharmacol. 2004 PMID: 15302681
Lee The novel phospholipase C activator, m-3M3FBS, induces monocytic leukemia cell apoptosis. Cancer Lett. 2005 PMID: 15863272
Bae Identification of a compound that directly stimulates phospholipase C activity. Mol.Pharmacol. 2003 PMID: 12695532