LY 235959
Tocris Bioscience, part of Bio-Techne | Catalog # 1019
Competitive NMDA antagonist
Discontinued Product
1019 has been discontinued.
View all NMDA Receptor Antagonists products.
Product Description
LY 235959 is a competitive NMDA receptor antagonist.Licensing Information
Sold with the permission of Eli Lilly and Company.Product Specifications
Molecular Weight
277.26
Formula
C11H20NO5P
Storage
Desiccate at +4°C
Chemical Name
[3S-(3α,4aα,6β,8aα)]-Decahydro-6-(phosphonomethyl)-3-isoquinolinecarboxylic acid)
CAS Number
137433-06-8
PubChem ID
131938
InChI Key
STIRHCNEGQQBOY-QEYWKRMJSA-N
SMILES
[H][C@]12[C@](CC[C@H](CP(O)(O)=O)C2)([H])CN[C@H]([C@](O)=O)C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 100 |
Preparing Stock Solutions
for LY 235959
The following data is based on the product molecular weight 277.26
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.61 mL | 18.03 mL | 36.07 mL |
| 5 mM | 0.72 mL | 3.61 mL | 7.21 mL |
| 10 mM | 0.36 mL | 1.80 mL | 3.61 mL |
| 50 mM | 0.07 mL | 0.36 mL | 0.72 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Ellison Competitive and non-competitive NMDA antagonists induce similar limbic degeneration. Neuroreport 1994 PMID: 7696633
- Borowicz Competitive NMDA-receptor antagonists, LY 235959 and LY 233053, enhance the protective efficacy of various antiepileptic drugs against maximal electroshock-induced seizures in mice. Epilepsia 1996 PMID: 8681893
Product Specific Notices for LY 235959
For research use only
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