LTURM 36
Tocris Bioscience, part of Bio-Techne | Catalog # 5835
PI 3-kinase δ inhibitor
Discontinued Product
5835 has been discontinued.
View all PI 3-Kinase Inhibitors products.
Product Description
LTURM 36 is a PI 3-kinase δ inhibitor (IC50 values are 0.64 and 5.0 μM for PI-3Kδ and PI3Kβ, respectively). Exhibits anticancer activity in a renal cancer cell line.Product Specifications
Molecular Weight
358.39
Formula
C22H18N2O3
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
2-(4-Morpholinyl)-8-(1-naphthalenyl)-4H-1,3-benzoxazin-4-one
CAS Number
1879887-94-1
PubChem ID
122705988
InChI Key
HSONTPGVHUWDEY-UHFFFAOYSA-N
SMILES
O=C1C2=C(C(C3=CC=CC4=C3C=CC=C4)=CC=C2)OC(N5CCOCC5)=N1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 35.84 | 100 |
Preparing Stock Solutions
for LTURM 36
The following data is based on the product molecular weight 358.39
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.79 mL | 13.95 mL | 27.90 mL |
| 5 mM | 0.56 mL | 2.79 mL | 5.58 mL |
| 10 mM | 0.28 mL | 1.40 mL | 2.79 mL |
| 50 mM | 0.06 mL | 0.28 mL | 0.56 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Morrison Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines. Eur.J.Med.Chem. 2016 PMID: 26854431
Product Specific Notices for LTURM 36
For research use only
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