Loratidine

Tocris Bioscience, part of Bio-Techne | Catalog # 1944

Peripheral H1 antagonist; antiallergic agent
Discontinued Product
1944 has been discontinued. View all Histamine H1 Receptor Antagonists products.

Key Product Details

Description

Peripheral H1 antagonist; antiallergic agent

Alternative Names

SCH 29851

View all Histamine H1 Receptor Antagonists »

Product Description

Loratidine is a peripheral histamine H1 receptor antagonist (Ki = 35 nM); devoid of central effects. Orally active antiallergic agent.

Product Specifications

Molecular Weight

382.88

Formula

C22H23ClN2O2

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester

CAS Number

79794-75-5

PubChem ID

3957

InChI Key

JCCNYMKQOSZNPW-UHFFFAOYSA-N

SMILES

CCOC(=O)N1CC\C(CC1)=C1/C2=NC=CC=C2CCC2=C1C=CC(Cl)=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 9.57 25
Ethanol 38.29 100

Preparing Stock Solutions for Loratidine

The following data is based on the product molecular weight 382.88

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.61 mL 13.06 mL 26.12 mL
5 mM 0.52 mL 2.61 mL 5.22 mL
10 mM 0.26 mL 1.31 mL 2.61 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Loratidine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Loratidine

For research use only

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