LF 11

Name: LF 11
Brand: Tocris Bioscience
SKU: 4421
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 4421

(1)

COA / SDS

Antibiotic; neutralizes LPS

Discontinued Product

4421 has been discontinued. View all Antibiotics products.

Key Product Details

Description:	Antibiotic; neutralizes LPS
Molecular Weight:	1529.81

View Full Technical Details for LF 11

Technical Data
Citations / Reviews (1)

Biological Activity for LF 11

LF 11 is a peptide based on the lipopolysaccharide (LPS)-binding region of human lactoferricin. Neutralizes LPS; displays antimicrobial activity against Gram-negative and Gram-positive bacteria. Analog lauryl-LF 11 (Cat. No. 4422) available.

Technical Data for LF 11

M. Wt	1529.81
Formula	C₆₉H₁₁₂N₂₆O₁₄
Single Letter Sequence	FQWQRNIRKVR (Modifications: Arg-11 = C-terminal amide)
Storage	Store at -20°C
CAS Number	832729-13-2
PubChem ID	25089955
InChi Key	SIROSQHTQDVQTI-JDJCIBPGSA-N
Smiles	[H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for LF 11

References are publications that support the biological activity of the product.

Japelj Structural origin of endotoxin neutralization and antimicrobial activity of a lactoferrin-based peptide. J.Biol.Chem. 2005 PMID: 15687491
Andra Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 2005 PMID: 15344905
Sanchez-Gomez Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides. BMC Mirobiol. 2008 PMID: 19014450

LF 11

Tocris Bioscience, part of Bio-Techne | Catalog # 4421

Key Product Details

Biological Activity for LF 11

Technical Data for LF 11

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for LF 11

Product Documents for LF 11

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

Stay Connected