L-Glutamic acid
Tocris Bioscience, part of Bio-Techne | Catalog # 0218
Endogenous, non-selective glutamate receptor agonist
Key Product Details
Description
Endogenous, non-selective glutamate receptor agonist
Product Description
L-Glutamic acid is a the predominant excitatory transmitter in the mammalian central nervous system. L-Glutamic acid acts at ionotropic and metabotropic glutamate receptors.MNI-caged-L-glutamate (Cat. No. 1490) also available.
Product Specifications
Molecular Weight
147.13
Formula
C5H9NO4
Storage
Store at RT
Chemical Name
(S)-1-Aminopropane-1,3-dicarboxylic acid
CAS Number
56-86-0
PubChem ID
33032
InChI Key
WHUUTDBJXJRKMK-VKHMYHEASA-N
SMILES
[H][C@@](CCC(O)=O)(N)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1eq. NaOH | 100 |
Preparing Stock Solutions
for L-Glutamic acid
The following data is based on the product molecular weight 147.13
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.80 mL | 33.98 mL | 67.97 mL |
| 5 mM | 1.36 mL | 6.80 mL | 13.59 mL |
| 10 mM | 0.68 mL | 3.40 mL | 6.80 mL |
| 50 mM | 0.14 mL | 0.68 mL | 1.36 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Watkins and Evans Excitatory amino acid transmitters. Annu.Rev.Pharmacol.Toxicol. 1981 PMID: 6112965
- Yang and Stockwell Ferroptosis: Death by lipid peroxidation. Trends Cell Biol. 2016 PMID: 26653790
- Monaghan The excitatory amino acid receptors: their classes, pharmacology and distinct properties in the function of the central nervous system. Annu.Rev.Pharmacol.Toxicol. 1989 PMID: 2543272
Product Specific Notices for L-Glutamic acid
For research use only
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