KY 02111

Tocris Bioscience, part of Bio-Techne | Catalog # 4731

Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
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Key Product Details

Description

Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes

View all Compounds for Stem Cell Differentiation »

Product Description

KY 02111 promotes differentiation of human ESCs and iPSCs into cardiomyocytes when used after day three in culture; differentiation efficiency increases when used after initial culture with CHIR 99021 (Cat. No. 4423). Induces downregulation of Wnt signaling target genes; inhibits canonical Wnt signaling in a manner distinct from other known Wnt inhibitors.

Product Specifications

Molecular Weight

376.86

Formula

C18H17ClN2O3S

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide

CAS Number

1118807-13-8

PubChem ID

8582409

InChI Key

LXFKEVQQSKQXPR-UHFFFAOYSA-N

SMILES

O=C(CCC3=CC=C(OC)C(OC)=C3)NC2=NC1=CC=C(Cl)C=C1S2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 18.84 50

Preparing Stock Solutions for KY 02111

The following data is based on the product molecular weight 376.86

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 5.31 mL 26.54 mL 53.07 mL
2.5 mM 1.06 mL 5.31 mL 10.61 mL
5 mM 0.53 mL 2.65 mL 5.31 mL
25 mM 0.11 mL 0.53 mL 1.06 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for KY 02111

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for KY 02111

For research use only

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