Jedi2
Tocris Bioscience, part of Bio-Techne | Catalog # 6614
Piezo1 channel activator
Product Description
Jedi2 is a piezo1 channel activator. Promotes Ca2+ influx into HEK293 cells expressing Piezo1 channels. Elicits responses in mouse Piezo1-transfected, but not Piezo2-transfected cells.Product Specifications
Molecular Weight
208.23
Formula
C10H8O3S
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
CAS Number
651005-90-2
PubChem ID
2796026
InChI Key
YXDCRSXNEOKXDE-UHFFFAOYSA-N
SMILES
CC1=C(C(O)=O)C=C(C2=CC=CS2)O1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 20.82 | 100 | |
| Ethanol | 20.82 | 100 |
Preparing Stock Solutions
for Jedi2
The following data is based on the product molecular weight 208.23
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.80 mL | 24.01 mL | 48.02 mL |
| 5 mM | 0.96 mL | 4.80 mL | 9.60 mL |
| 10 mM | 0.48 mL | 2.40 mL | 4.80 mL |
| 50 mM | 0.10 mL | 0.48 mL | 0.96 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Wang A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel. Nat.Commun. 2018 PMID: 29610524
Product Specific Notices for Jedi2
For research use only
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