ISOX INACT
Tocris Bioscience, part of Bio-Techne | Catalog # 5808
Negative control for PF-CBP1
Discontinued Product
5808 has been discontinued.
View all Bromodomain Inhibitors products.
Product Description
ISOX INACT is a negative control for PF CBP1. Exhibits negligible activity at CBP and BRD4.Active Analog also available.
Licensing Information
Sold for research purposes under agreement from Pfizer Inc.Product Specifications
Molecular Weight
488.62
Formula
C29H36N4O3
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
5-(Dimethyl-1,2-oxazol-4-yl)-2-[2-(4-methoxyphenyl)ethyl]--4,6-dimethyl-1-[2-(morpholin-4-yl)ethyl]-1H-1,3-benzodiazole
PubChem ID
121237856
InChI Key
FTOHXUPHICJSCR-UHFFFAOYSA-N
SMILES
CC(ON=C1C)=C1C2=C(C)C(N=C(CCC3=CC=C(OC)C=C3)N4CCN5CCOCC5)=C4C=C2C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 24.43 | 50 | |
| Ethanol | 9.77 | 20 |
Preparing Stock Solutions
for ISOX INACT
The following data is based on the product molecular weight 488.62
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 4.09 mL | 20.47 mL | 40.93 mL |
| 2.5 mM | 0.82 mL | 4.09 mL | 8.19 mL |
| 5 mM | 0.41 mL | 2.05 mL | 4.09 mL |
| 25 mM | 0.08 mL | 0.41 mL | 0.82 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Chekler Transcriptional profiling of a selective CREB binding protein bromodomain inhibitor highlights therapeutic opportunities. Chem.Biol. 2015 PMID: 26670081
Product Specific Notices for ISOX INACT
For research use only
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